Clinical studies
As a veterinarian
As a pet owner
As a veterinarian
As a veterinarian, taking part in clinical trials proposed by OCRVet represents a major opportunity for
- Access to innovative therapies
- Extending access to veterinary care
- Greater visibility with your customers
- Developing additional expertise
- Growth of your clinic and network
- Opportunities for scientific publications
- Contribute to research and develop knowledge
As a pet owner
As a pet owner, taking part in a clinical study offers :
- Access to innovative treatments for your pet
- An enhanced medical monitoring for your pet
- A contribution to advances in veterinary and human medicine
- Free diagnostic and therapeutic care for your sick pet
Do not hesitate to discuss this with your veterinarian or contact the OCRvet project coordinator.
Dog
Innovative immunotherapy treatment for canine tumors
In progress
Cancerology
Study description / objectives
Assessing the efficacy and safety of treatment in companion dogs with metastatic, recurrent or resistant cancer
Indication
Carcinoma, adenocarcinoma, soft tissue sarcomas
Main outcome
Assessing objective tumour response and the safety of immunotherapy treatment
Participation period
10 to 12 weeks
Evaluation
Clinical examinations • Blood and urine tests • Tumour imaging
Cat
Anxious cats
In progress
Behaviour
Study description / objectives
Assessing the effectiveness of a food complement in improving behaviour in anxious cats
Indication
Anxious cat
Main outcome
Reduction of anxiety-related behavioural symptoms in cats
Participation period
2 months
Evaluation
Behaviour and quality of life questionnaires • Biological assays
Dog
Oral treatment for osteoarthritis in dogs
Finished
Arthrosis
Study description / objectives
Assessing the efficacy and tolerability of a treatment for osteoarthritis in dogs
Indication
Osteoarthritis
Main outcome
Evaluation of the efficacy of treatment in reducing symptoms associated with osteoarthritis
Participation period
3 months
Evaluation
Clinical, blood and urine examination • Veterinary/owner forms • Activity monitor
Dog
Oral treatment for cerebral gliomas
In progress
Cancerology
Study description / objectives
Assessing tumour response and safety of oral treatment in high-grade gliomas
Indication
Suspicion of high-grade glioma
Main outcome
Evaluating tumour response and the safety of oral treatment
Participation period
84 days
Evaluation
Clinical, neurological and biological examination (blood samples) • MRI
Dog
Innovative immunotherapy for solid tumors
In progress
Cancerology
Study description / objectives
Assessing the safety and preliminary efficacy of oncolytic immunotherapy in dogs with malignant tumours accessible to intra-tumoral injection
Indication
Solid tumor of the head and neck, skin tumor, melanoma, breast carcinoma, sarcoma
Main outcome
Assessment of tumor and immune response Assessment of maximum tolerated dose
Participation period
6 to 10 weeks
Evaluation
Clinical examinations • Biopsies • CT scan • Biological samples • Quality of life questionnaire
Dog
Medical device for capturing circulating tumor cells
In progress
Cancerology
Study description / objectives
Assessing the safety and efficacy of a medical device for capturing circulating tumor cells (CTCs)
Indication
Dog suffering from metastatic carcinoma
Main outcome
Assess the safety of the CTC capture procedure and device during blood filtration
Participation period
1 to 2 visits
Evaluation
Clinical examinations • Imagery • Taking blood samples • Monitoring vital signs
Dog
Dog requiring TPLO surgery / maxillofacial surgery / hip prosthesis fitting
Future
Orthopedic surgery
Study description / objectives
Assessing the safety and efficacy of a new TPLO plate
Indication
Dog with cruciate ligament rupture requiring TPLO surgery
Main outcome
To assess the effectiveness of a new TPLO plate in preserving the function of the operated limb using a veterinary score up to 16 weeks post-op
Participation period
4 mois
Evaluation
Clinical examinations • Imaging – Blood samples • Veterinary/owner questionnaires • Walking analysis platform (optional)
Cat
Food supplement for pre-diabetic cats
In progress
Diabetes
Study description / objectives
Assessing the long-term safety and efficacy of a dietary supplement in cats that have spontaneously developed pre-diabetes
Indication
Pre-diabetic cat or cat in remission from diabetes
Main outcome
Evaluate the efficacy of the food supplement by assessing blood parameters
Participation period
2 months
Evaluation
Clinical examination • Taking blood and urine samples • Follow-up with a proprietary notebook
Dog
Dog suffering from osteoarthritis of the elbow or stifle
In progress
Arthrosis
Study description / objectives
To confirm the efficacy and safety of the investigational product in the treatment of osteoarthritis of the elbow or stifle in dogs
Indication
Dog with osteoarthritis of the elbow or stifle
Main outcome
To assess the effectiveness of the investigational product in reducing the severity of osteoarthritis symptoms, in particular a reduction in pain and an improvement in mobility
Participation period
3 months
Evaluation
Clinical examinations • Veterinary/owner questionnaires
Dog
Food supplement for dogs suffering from articulation problems
In progress
Arthrosis
Study description / objectives
Assessing the safety and efficacy of a dietary supplement in dogs suffering from spontaneous joint problems
Indication
Dogs suffering from spontaneous articulation problems
Main outcome
Determine the preferred dose of the dietary supplement for the future phase II study
Participation period
70 to 84 days
Evaluation
Clinical examinations • Blood samples • Veterinary/owner questionnaires • Daily activity monitoring using an activity collar
Dog
Atopic dermatitis
In progress
Dermatology
Study description / objectives
Assessing the efficacy and safety of a new treatment for atopic dermatitis
Indication
Atopic dermatitis
Main outcome
To assess the efficacy of the treatment in reducing the symptoms of atopic dermatitis, as well as its tolerability.
Participation period
1 month to 4 months depending on the group
Evaluation
Clinical (clinical examination, questionnaires) • Biological (blood and urine samples)
Cat
Feline periodontal disease
In progress
Dentistry
Study description / objectives
Assessing the efficacy and tolerability of a treatment to reduce alveolar bone loss associated with periodontal disease in cats
Indication
Feline periodontal disease
Main outcome
Assess the plasma level of a bone resorption marker
Participation period
3 months
Evaluation
Clinical examinations • Biological analyses • Dental X-rays
Dog
Gastroparesis
In progress
Gastro-enterology
Study description / objectives
Evaluating the tolerance and efficacy of a treatment for gastroparesis in dogs and measuring the improvement in quality of life
Indication
Gastroparesis (delayed gastric emptying without mechanical obstruction)
Main outcome
Evaluate the frequency of vomiting
Participation period
1 months
Evaluation
Clinical examinations • Blood and urine tests • Owners’ questionnaires
Cat
Coprostasis cats
Future
Gastro-enterology
Study description / objectives
Evaluate the tolerability and efficacy of the treatment in reducing the symptoms of coprostasis and improving the cats’ quality of life.
Indication
Chronic coprostasis
Main outcome
Evaluate stool frequency
Participation period
1 month
Evaluation
Clinical examinations • Blood and urine tests • Owners’ questionnaires
